Wednesday, December 14, 2011

DNA and RNA Structure and Function (Basics)

All cellular life is made of double stranded DNA.

In bacteria, the origin of replication is close to where the bacterial cell genome is anchored by the kinetichore to the cell wall.

Negatively supercoiled loop domains fit well inside a bacterial cell, and are easily transcribed. There is no scaffold in bacteria.


DNA is compacted into fibers using histones, or basic, positively charged proteins that attacks to DNA to bind it. One nucleosome is made up of two of each of the following four core histone proteins, H2A, H2B, H3, H4. H1 is not used in a histone octamer. The histone wraps DNA around itself. H1 is often seen between histone octamers.

No comments:

Post a Comment